THE EFFECTS OF HALOTHANE AND ETHER ON THE PULMONARY CIRCULATION IN THE INNERVATED PERFUSED CAT LUNG
Open Access
- 1 April 1977
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 49 (4) , 309-314
- https://doi.org/10.1093/bja/49.4.309
Abstract
The effects of halothane and diethyl ether on pulmonary vascular resistance and the pulmonary vasoconstrictor response to alveolar hypoxia were studied in the innervated perfused cat lung. A left and right heart bypass technique was used to allow perfusion of the lungs at constant flow. Neither anaesthetic agent caused a significant change in pulmonary vascular resistance but both agents caused a depression of the pulmonary vasoconstrictor response to hypoxia.Keywords
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