Influence of Ibuprofen on Haemostasis in Patients on Anticoagulant Therapy
- 1 March 1973
- journal article
- research article
- Published by SAGE Publications in Journal of International Medical Research
- Vol. 1 (3) , 180-183
- https://doi.org/10.1177/030006057300100307
Abstract
A group of 50 patients on warfarin sodium were studied for possible adverse effects on anticoagulant action when ibuprofen was administered concomitantly. Factors II, VII and X were determined before starting and after seven days on ibuprofen therapy. Ibuprofen was not found to adversely affect the anticoagulant activity of warfarin. A further study in 30 normal volunteers (on no drugs) suggests that 600 mg ibuprofen daily for 3 days has no action of its own in the plasma phase of haemostasis.Keywords
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