Effects of age on apparent31P spin–lattice relaxation times of rat brain phosphates

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Abstract
Apparent 31P spin–lattice relaxation times have been measured in vivo for brain phosphates in young adult, mature adult, and aged rats at 4.7 T and 35°C. Statistically significant differences were found for most phosphate species, except PCr and y-ATP, among the three age groups, particularly between the young and mature adults. Age-related changes in tissue composition and exchange reactions are discussed as possible contributors to these results. © 1987 Academic Press, Inc.