Kininogenase Activity in Rat Uterus Homogenates
- 1 January 1982
- journal article
- research article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 363 (2) , 1359-1364
- https://doi.org/10.1515/bchm2.1982.363.2.1359
Abstract
A synthetic peptide substrate for tissue kallikreins was hydrolyzed by uterus homogenates. These also released kinins when incubated with dog kininogen. By using high pressure liquid chromatography in combination with a radioimmunoassay for kinins, the peptides released were identified as bradykinin and kallidin. Plasma kallikrein and trypsin released bradykinin from dog kininogen and hog pancreas kallikrein released kallidin from this substrate. A tissue kallikrein and also a trypsin-like enzyme or perhaps plasma kallikrein are present in rat uterus.This publication has 7 references indexed in Scilit:
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