Nonrandom X-Chromosome Inactivation—an Artifact of Cell Selection
- 1 January 1972
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 69 (1) , 37-39
- https://doi.org/10.1073/pnas.69.1.37
Abstract
The present study shows that a high degree of variability in the distribution of XX and XY cells exists among various tissues of artificially assembled or spontaneously occurring mouse chimeras. This variation from the expected equal distribution in various tissues of an animal may have resulted from random distribution, unequal segregation, or selective differences of such cells during development. This variation may also explain the observed intertissue and interanimal variations in the distribution of inactive paternal and maternal X-chromosomes in some mammalian females.Keywords
This publication has 14 references indexed in Scilit:
- Non-Random Late Replication of X Chromosomes in Mules and HinniesNature, 1971
- Evidence for Selective Differences between Cells with an Active Horse X Chromosome and Cells with an Active Donkey X Chromosome in the Female MuleNature, 1971
- Cytological and Biochemical Correlation of Late X-Chromosome Replication and Gene Inactivation in the MuleProceedings of the National Academy of Sciences, 1971
- Phosphoglycerate Kinase Polymorphism in Kangaroos provides Further Evidence for Paternal X InactivationNature New Biology, 1971
- Late DNA Replication in the Paternally Derived X Chromosome of Female KangaroosNature, 1971
- Non-random X-Inactivation in the Female MuleNature, 1969
- THE MURINE Y CHROMOSOME AS A MARKERTransplantation, 1966
- Cromosomes of the horse, the donkey, and the muleChromosoma, 1962
- Mouse Chimæras Developed from Fused EggsNature, 1961
- Cytological identification of male and female somatic cells in the mouseExperimental Cell Research, 1960