Effect of structural modification on the inhibitory selectivity of rutaecarpine derivatives on human CYP1A1, CYP1A2, and CYP1B1
- 11 June 2003
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 13 (15) , 2535-2538
- https://doi.org/10.1016/s0960-894x(03)00469-4
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- The Alkaloid Rutaecarpine Is a Selective Inhibitor of Cytochrome P450 1A in Mouse and Human Liver MicrosomesDrug Metabolism and Disposition, 2002
- Design, Synthesis, and Discovery of Novel trans-Stilbene Analogues as Potent and Selective Human Cytochrome P450 1B1 InhibitorsJournal of Medicinal Chemistry, 2001
- Regulation, Function, and Tissue-Specific Expression of Cytochrome P450 CYP1B1Annual Review of Pharmacology and Toxicology, 2001
- Molecular modelling of CYP1 family enzymes CYP1A1, CYP1A2, CYP1A6 and CYP1B1 based on sequence homology with CYP102Published by Elsevier ,1999
- Selectivity of Polycyclic Inhibitors for Human Cytochrome P450s 1A1, 1A2, and 1B1Chemical Research in Toxicology, 1998
- Quantitative Structure-Activity Relationships in Substrates, Inducers, and Inhibitors of Cytochrome P4501 (CYP1)Drug Metabolism Reviews, 1997
- Human Cytochrome P450 Enzymes: A Status Report Summarizing Their Reactions, Substrates, Inducers, and InhibitorsDrug Metabolism Reviews, 1997
- Synthesis of rutaecarpine and cytotoxic analoguesBioorganic & Medicinal Chemistry Letters, 1995
- Human Cytochrome P450 EnzymesPublished by Springer Nature ,1995
- Studies of rutaecarpine and related quinazolinocarboline alkaloidsThe Journal of Organic Chemistry, 1985