HTLV seroepidemiology in a central African population with high incidence of tropical spastic paraparesis
Open Access
- 1 July 1990
- journal article
- Published by Oxford University Press (OUP) in Transactions of the Royal Society of Tropical Medicine and Hygiene
- Vol. 84 (4) , 577-579
- https://doi.org/10.1016/0035-9203(90)90046-h
Abstract
In Lisala (Equateur region, Zaire), where a cluster of tropical spastic paraparesis/HTLV-1 associated myelopathy (TSP/HAM) was described, (14%) out-patients and hospital personnel were HTLV antibody positive. No differences in prevalences were observed between out-patients and hospital personnel or between ethnic groups. The annual attack rate of TSP/HAM is estimated at 0·15-0·3 per 1000 infected. The ethnic and familial clustering of TSP/HAM together with the high attack rate suggests the presence of co-factors for the progression to disease. This high prevalence of HTLV antibodies contrasts with the low prevalence in another part of the Equateur region.Keywords
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