ANTIBIOTICS IN DISEASES OF THE BILIARY TRACT

Publisher Website
Google Scholar
Abstract
As new antibiotic or chemotherapeutic agents have been introduced into the therapeutic armamentarium, many of them have been used in the treatment of biliary tract disease. Improvement observed following the use of these drugs has often been attributed to them. This has been due to the fact that each of these drugs, in the course of pharmacological observations, has been shown to be excreted into the normal biliary tract of lower animals or humans. Until I began to study the excretion and concentration of antibiotic and chemotherapeutic agents in the abnormal human biliary tract, no one had approached the problem from that aspect. Since that time I have studied the excretion and concentration of the sulfonamides, penicillin, streptomycin, aureomycin, and, more recently, oxytetracycline (Terramycin). As a result of these investigations it became apparent that the excretion and concentration in the abnormal biliary tract was entirely different from that in the

This publication has 0 references indexed in Scilit: