ENANTIOSELECTIVE ESTER HYDROLYSIS CATALYZED BY A MICELLAR MODEL OF ZINC ENZYMES

5 November 1982

journal article
research article
Published by Oxford University Press (OUP) in Chemistry Letters

Vol. 11 (11) , 1875-1878
https://doi.org/10.1246/cl.1982.1875

Abstract

N-Laurylimidazoles containing L-2-pyrrolidinemethanol function gave large rate enhancements [k_obsd^a(L)/k_obsd^o(L)=56–401] and reasonable enantioselectivities[k_obsd^a(L)/k_obsd^a(D)=1.40–3.92] in the presence of zinc ion and CTABr micelle for the hydrolysis of p-nitrophenyl L-and D-N-benzyloxycarbonylphenylalanates.

Keywords

ZINC
ENZYME

This publication has 1 reference indexed in Scilit:

Peptide Syntheses Via Amino Acid Active Esters¹
Journal of the American Chemical Society, 1959