The Heart in Systemic Sclerosis

Abstract
Scleroderma is well characterized as a fibrotic disorder that is either localized or generalized in extent; when it is localized it is called morphea, or linear scleroderma, and there are essentially no systemic implications; when it is generalized, the term "systemic sclerosis" is used, and the target organs are the skin, gut, lungs, heart, and kidneys.1 Three types of generalized scleroderma can be distinguished: diffuse systemic sclerosis, and two types of limited cutaneous systemic sclerosis (sclerodactyly and acrosclerosis). Patients with diffuse systemic sclerosis (20 per cent) may be identified by the simultaneous onset of vasospastic (Raynaud's phenomenon) and cutaneous (puffy, . . .

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