Reactive Oxygen Species Play an Important Role in the Activation of Heat Shock Factor 1 in Ischemic-Reperfused Heart
- 23 February 1999
- journal article
- other
- Published by Wolters Kluwer Health in Circulation
- Vol. 99 (7) , 934-941
- https://doi.org/10.1161/01.cir.99.7.934
Abstract
Background—The myocardial protective role of heat shock protein (HSP) has been demonstrated. Recently, we reported that ischemia/reperfusion induced a significant activation of heat shock factor (H...Keywords
This publication has 40 references indexed in Scilit:
- Transgenic mice expressing the human heat shock protein 70 have improved post-ischemic myocardial recovery.Journal of Clinical Investigation, 1995
- Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury.Journal of Clinical Investigation, 1995
- Activation of heat-shock transcription factor by graded reductions in renal ATP, in vivo, in the rat.Journal of Clinical Investigation, 1994
- Induction of stress proteins in cultured myogenic cells. Molecular signals for the activation of heat shock transcription factor during ischemia.Journal of Clinical Investigation, 1992
- Analysis of RNA for transcripts for catalase and SP71 in rat hearts after in vivo hyperthermiaBiochemistry and Cell Biology, 1991
- Rapid expression of heat shock protein in the rabbit after brief cardiac ischemia.Journal of Clinical Investigation, 1991
- Effects of exogenous free radicals on electromechanical function and metabolism in isolated rabbit and guinea pig ventricle. Implications for ischemia and reperfusion injury.Journal of Clinical Investigation, 1989
- Synthesis of stress proteins in rat cardiac myocytes 2-4 days after imposition of hemodynamic overload.Journal of Clinical Investigation, 1988
- Reduced vulnerability of the hypertrophied rat heart to oxygen-radical injuryCanadian Journal of Physiology and Pharmacology, 1987
- Allopurinol and oxypurinol are hydroxyl radical scavengersFEBS Letters, 1987