Biophysical Characterization of Infectious Bovine Rhinotracheitis Virus

Abstract
The agent of infectious bovine rhinotracheitis virus, an acute respiratory disease of cattle, has been studied by ultracentrifugation and electron microscopical methods. Particles of 145-156 m[mu] diameter were associated with infectivity, while electron microscopy of infectious fluids revealed 136 [mu] 10 m[mu] diameter particles. Infected cells in tissue culture showed intracellular particles of the same size.
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