Risks Associated with Exchange Transfusion

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Abstract
ALTHOUGH most medical centers perform exchange transfusions on newborn infants if the bilirubin reaches levels of 18 to 20 mg. per 100 ml. in the first few days of life1 2 3 4 there are many who doubt its necessity as a routine procedure at these levels.5 6 7 8 Since the decision to perform an exchange transfusion is based essentially on the risks inherent in the procedure itself versus those associated with the concentration of serum bilirubin, more precise knowledge of these hazards would enable the operator to make his decision on a more rational basis. Moreover, there is still wide variation in the literature . . .