Lymphocyte transformation and leucocyte migration-inhibition by Australia antigen.

  • 1 September 1973
    • journal article
    • Vol. 15  (1) , 27-34
Abstract
The occurrence of a state of cell-mediated immune responsiveness to the Australia antigen following acute virus-B hepatitis has been demonstrated by the use of two in vitro methods—the lymphocyte transformation test and the leucocyte migration–inhibition test. Australia antigen-rich serum and purified Australia antigen were found to be effective agents in both tests. Close correlation was observed between the two tests. Persistent carriers of the Australia antigen give negative results with both tests.