Probing protein conformation by a combination of electrospray mass spectrometry and molecular modelling
- 1 January 1992
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 10,p. 761-764
- https://doi.org/10.1039/c39920000761
Abstract
Electrospray-ionisation mass spectrometry and molecular modelling have been used to probe two conformations of tuna cytochrome c; the number of protons which could be exchanged by deuterons was in remarkable agreement with that calculated using an algorithm for the determination of solvent-accessible surface.Keywords
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