Diabetic Microangiopathy and the Control of Blood Glucose

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Abstract
With varying degrees of success almost all physicians attempt to maintain approximately normal blood glucose levels in their diabetic patients, in the hope that good control will delay and perhaps prevent the microangiopathic manifestations of diabetes. Nonetheless, as amply demonstrated by conflicting editorials in the Journal 1 , 2 and even more convincingly by the numerous publications on the subject over the past two years, the question whether tight control of blood glucose influences the microvascular complications of diabetes still remains unanswered.If moderate reductions in blood glucose levels were all that were necessary to prevent the clinical manifestations of diabetic microangiopathy, this . . .