Inhibition of human sputum elastase by 7-substituted 5-methyl-2-isopropylamino-4H-3, 1-benzoxazin-4-ones
- 1 July 1994
- journal article
- research article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 48 (2) , 426-428
- https://doi.org/10.1016/0006-2952(94)90117-1
Abstract
No abstract availableKeywords
This publication has 10 references indexed in Scilit:
- Potential Problems in Designing Elastase Inhibitors for TherapyAmerican Review of Respiratory Disease, 1991
- Design and synthesis of 4H-3,1-benzoxazin-4-ones as potent alternate substrate inhibitors of human leukocyte elastaseJournal of Medicinal Chemistry, 1990
- Mechanism for slow-binding inhibition of human leukocyte elastase by valine-derived benzoxazinonesBiochemistry, 1987
- Inhibition of serine proteases by benzoxazinones: effects of electron withdrawal and 5-substitutionBiochemical and Biophysical Research Communications, 1986
- Elastase in Tissue InjuryAnnual Review of Medicine, 1985
- A new class of heterocyclic serine protease inhibitors. Inhibition of human leukocyte elastase, porcine pancreatic elastase, cathepsin G, and bovine chymotrypsin A alpha with substituted benzoxazinones, quinazolines, and anthranilates.Journal of Biological Chemistry, 1982
- Kinetics of association of serine proteinases with native and oxidized alpha-1-proteinase inhibitor and alpha-1-antichymotrypsin.Journal of Biological Chemistry, 1980
- Mapping the extended substrate binding site of cathepsin G and human leukocyte elastase. Studies with peptide substrates related to the alpha 1-protease inhibitor reactive site.Journal of Biological Chemistry, 1979
- Proteases from purulent sputum. Purification and properties of the elastase and chymotrypsin-like enzymes.Journal of Biological Chemistry, 1977
- Tight-binding inhibitors—IBiochemical Pharmacology, 1975