Potassium permeability of the mesothelium of the frog mesentery
- 1 February 1979
- journal article
- research article
- Published by Wiley in Acta Physiologica Scandinavica
- Vol. 105 (2) , 228-238
- https://doi.org/10.1111/j.1748-1716.1979.tb06335.x
Abstract
The mesothelium of the mesentery is a single cell layer described to offer no or every little hindrance to diffusion of small water soluble solutes. We have measured the potassium permeability of the mesothelium of the frog mesentery both in vivo and in vitro. The permeability measured in vivo–using K+–sensitive microelectrodes is 2.4 times 10-5 cm s-1. In vitro measurements using conventional tracer flux technique on isolated mesentery yields a K+-permeability of 5.7 times 10-5 cm s_1. These values are 15–30 times smaller than values previously reported from in vitro experiments on rat and rabbit mesentery. Also, the permeability is 12–15 times lower than the K+-permeability of the capillary wall determined on single capillaries in the frog mesentery. In the frog mesentery the mesothelium thus represents an important diffusion barrier compared to the capillary wall. This may be critical in experiments where filtration and reflexion coefficients of the capillaries are determined from measurements of fluid exchange across the capillary wall in response to application of hypertonic solutions on the surface of the mesentery.Keywords
This publication has 9 references indexed in Scilit:
- The permeability of single capillaries to potassium ions.The Journal of general physiology, 1978
- Osmotic reflextion coefficients of capillary walls to low molecular weight hydrophilic solutes measured in single perfused capillaries of the frog mesentery.The Journal of Physiology, 1976
- Transmembrane Ion Transport in Autoperfused Cat MesenteryPublished by Springer Nature ,1976
- Metabolic control of permeability in isolated mesenteryAmerican Journal of Physiology-Legacy Content, 1974
- Fluid movement rates through walls of single capillaries exposed to hypertonic solutionsAmerican Journal of Physiology-Legacy Content, 1971
- Permeability studies with the interstitial tissue of the rat mesenteryPflügers Archiv - European Journal of Physiology, 1971
- ‘Unstirred layers’ in frog skinThe Journal of Physiology, 1966
- Diffusional transport of solutes through mesentery and peritoneumJournal of Theoretical Biology, 1962