N -Acetyllactosamine Conjugated to Gold Nanoparticles Inhibits Enteropathogenic Escherichia coli Colonization of the Epithelium in Human Intestinal Biopsy Specimens
- 1 September 2006
- journal article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 74 (9) , 5419-5421
- https://doi.org/10.1128/iai.00739-06
Abstract
We previously reported that the bundle-forming pilus-mediated localized adherence of enteropathogenic Escherichia coli to HEp-2, T84, and Caco-2 cells is inhibited by N-acetyllactosamine neoglycoconjugates. The results presented here extend this observation to the epithelium of biopsy specimens obtained from the human adult duodenum, terminal ileum, and colon.Keywords
This publication has 28 references indexed in Scilit:
- Basis for N-acetyllactosamine-mediated inhibition of enteropathogenic Escherichia coli localized adherenceJournal of Medical Microbiology, 2006
- Temporal Expression of Enteropathogenic Escherichia coli Virulence Genes in an In Vitro Model of InfectionInfection and Immunity, 2005
- Enteropathogenic Escherichia coli Infection Triggers Host Phospholipid Metabolism PerturbationsInfection and Immunity, 2004
- Enteropathogenic Escherichia coli (EPEC) adhesion to intestinal epithelial cells: role of bundle-forming pili (BFP), EspA filaments and intiminMicrobiology, 2004
- Tails of two Tirs: actin pedestal formation by enteropathogenic E. coli and enterohemorrhagic E. coli O157:H7Current Opinion in Microbiology, 2003
- Cell Surface-localized Nucleolin Is a Eukaryotic Receptor for the Adhesin Intimin-γ of Enterohemorrhagic Escherichia coliO157:H7Journal of Biological Chemistry, 2002
- Pathogenesis and evolution of virulence in enteropathogenic and enterohemorrhagic Escherichia coliJournal of Clinical Investigation, 2001
- Intimin‐Mediated Tissue Specificity in EnteropathogenicEscherichia coliInteraction with Human Intestinal Organ CulturesThe Journal of Infectious Diseases, 2000
- Phosphatidylethanolamine recognition promotes enteropathogenic E. coli and enterohemorrhagic E. coli host cell attachmentMicrobial Pathogenesis, 1999
- A plasmid‐encoded type IV fimbrial gene of enteropathogenic Escherichia coli associated with localized adherenceMolecular Microbiology, 1992