THE DIRECT PERFUSION OF SURGICAL WOUNDS WITH LOCAL-ANESTHETIC SOLUTION - AN APPROACH TO POSTOPERATIVE PAIN

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  • 1 January 1983
    • journal article
    • research article
    • Vol. 65  (4) , 226-229
Abstract
A simple technique of wound perfusion with bupivacaine (Marcain) which provides sustained postoperative analgesia is described. No complications or side effects related to toxicity, hypersensitivity, infection or impaired wound healing were encountered. Postoperative pain was reduced and analgesic requirements were significantly lower in patients undergoing both intermittent (P < 0.01) and continuous (P = 0.1) wound perfusion (Student t test). Perfusion with isotonic saline was also effective. This may represent a true therapeutic effect attributable to the removal or dilution of pain mediating substances in the wound.