Poly(ADP-ribose) polymerase is a catalytic dimer and the automodification reaction is intermolecular.
Open Access
- 1 October 1993
- journal article
- abstracts
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 268 (30) , 22575-22580
- https://doi.org/10.1016/s0021-9258(18)41568-2
Abstract
No abstract availableKeywords
This publication has 31 references indexed in Scilit:
- Inhibition of DNA polymerase α, DNA polymerase β, terminal deoxynucleotidyl transferase, and DNA ligase II by poly(ADP-ribosyl)ation reaction in vitroPublished by Elsevier ,2004
- Mono(ADP-ribosyl)ation of poly(ADP-ribose)polymerase by cholera toxinBiochemical and Biophysical Research Communications, 1991
- Enzymological properties of poly(ADP-ribose)polymerase: characterization of automodification sites and NADase activityBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1991
- Poly(ADP-ribose) synthase is the major endogenous nonhistone acceptor for poly(ADP-ribose) in alkylated rat hepatoma cellsEuropean Journal of Biochemistry, 1987
- Nucleotide sequence of a full-length cDNA for human fibroblast poly(ADP-ribose) polymeraseBiochemical and Biophysical Research Communications, 1987
- Reaction mechanism for automodification of poly(ADP-ribos synthetaseBiochemical and Biophysical Research Communications, 1987
- Mechanisms of poly(ADP‐ribose) polymerase catalysis; mono‐ADP‐ribosylation of poly(ADP‐ribose) polymerase at nanomolar concentrations of NADFEBS Letters, 1986
- Two Proteolytic Degradation Products of Calf‐Thymus Poly(ADP‐ribose) Polymerase Are Efficient ADP‐ribose AcceptorsEuropean Journal of Biochemistry, 1983
- Relationship between nicotinamide adenine dinucleotide concentration and in vitro synthesis of poly(adenosine diphosphate ribose) on purified nucleosomesBiochemistry, 1980
- Enzyme-bound early product of purified poly(ADP-ribose) polymeraseBiochemical and Biophysical Research Communications, 1977