Relationship Between Atherosclerosis and Late-Life Depression

Open Access
Publisher Website
Google Scholar
Abstract
Several lines of evidence suggest that there is a relationship betweenvascular factors and late-life depression. Both symptomatic and silent braininfarcts are associated with subsequent depression.1 Furthermore,subtle white-matter and deep gray-matter abnormalities were found more frequentlyin depressed than in nondepressed persons.2 Avascular depression hypothesis has been proposed. It postulates that structuralchanges in the brain due to atherosclerosis are of primary importance in late-lifedepression.3,4

This publication has 18 references indexed in Scilit: