Roentgenologic, immunologic, and therapeutic study of erosive (inflammatory) osteoarthritis

Publisher Website
Google Scholar
Abstract
Erosive or inflammatory osteoarthritis refers to an inflammatory condition of the interphalangeal joints of the hand. Fifteen patients with erosive osteoarthritis were described. The principal clinical features are symmetrical synovitis of the interphalangeal joints of the hand, the knees and the first carpometacarpal, interphalangeal and metacarpophalangeal joints. The principal roentgenographic features are productive and destructive osseous changes. These changes, found particularly at the interphalangeal joints of the hand, consist of central and peripheral articular erosions and cysts associated with adjacent osteophyte formation. Serologic abnormalities commonly found in rheumatoid arthritis are rarely encountered. In 2/3 of the patients, the synovial fluid is noninflammatory; in the remainder, it is mildly to severely inflammatory. The injection of intra-articular corticosteroids predictably results in decreased synovitis but does not seem to affect the subsequent development of erosions.

This publication has 0 references indexed in Scilit: