FACILITATIVE AND DISRUPTIVE EFFECTS OF STRYCHNINE SULPHATE ON MAZE LEARNING

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Abstract
In two experiments initiated to determine the effect of strychnine sulphate on maze learning, two groups were injected with differing amounts and trained; in the subsequent study a control and low-strychnine dose group were replicated with Ss of another strain. The best low strychnine dose Ss made fewer errors than the best control or high strychnine dose Ss. Performance of worst high strychnine dose Ss was inferior to that of the worst control Ss. The findings are discussed in terms of known effects of strychnine on CNS activity.

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