The In Vivo Uptake of Vitamin B12by Intestinal Bacteria in Rats with Jejunal Blind Loops

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Abstract
57CoB12 was given orally to control rats and to rats with surgically created jejunal blind loops; and the radioactivity in washed small intestinal sediments was determined at timed intervals after the dose. The radioactivity in the sediments as a percentage of recovered radioactivity from small intestinal contents, and the amount of 57CoB12 per mg dried sediment were markedly increased in untreated blind-loop rats compared with control rats and with blind-loop rats treated orally with tetracyclin and lincomycin. In blind-loop rats there was a delay in gastric emptying and also a stagnation of radioactivity in the blind loop.