Is the Prescription of Amphetamine Justified as a Harm Reduction Measure?

Abstract
Although amphetamine is the most widely illicitly used drug in the United Kingdom after cannabis, relatively few proble matic users present to treatment agencies. Injecting ampheta mine users are a high risk group as far as HIV transmission is concerned. This paper reviews the first 3 years' operation of an oral amphetamine prescribing programme for injecting users. Over half the subjects ceased injecting, and there was a consid erable reduction in injecting by the remainder. 85% had not used or shared injecting equipment during the programme. However, subjects reported still using street amphetamine and offending, although at a lower rate than previously. There was little change in sexual practices. There was an increase in primary amphetamine users presenting for treatment. There is a case to be made that closely controlled and monitored programmes such as this can be justified on harm reduction grounds. A number of issues concerned with amphetamine prescribing are discussed.