CONTRIBUTIONS TO THE PHYSIOLOGY OF THE STOMACH

Abstract
The precise nature of the characteristic pain of peptic ulcer is a matter of some dispute. It is generally assumed to be dependent on and to bear a direct relation to gastric acidity. This view has seemed especially plausible in view of the alleviation of the pain by alkalies. Many textbooks and teachers state that the pain is due to direct irritation of the sensory nerve endings at the base of the ulcer by the acid or by mechanical means by invoking peristalsis. Still others believe the distress is caused by the acid bolus impinging against the pylorus. HAS THE STOMACH PAIN NERVES? Before discussing the irritating action of acidity or motility, we must consider the existing confusion regarding visceral pain in general and gastric pain in particular. The situation is well discussed in Hertz's work.1From observations in a case of gastric fistula, Carlson2concludes that the

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