The Mechanism of the Adjuvant Effect of Bordetella pertussis: the Substance Responsible for the Selective Enhancement of IgE Antibody Production
- 1 January 1974
- journal article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 47 (3) , 425-432
- https://doi.org/10.1159/000231235
Abstract
An investigation was made to find out the substance present in B. pertussis responsible for the enhancement of IgE antibody production in guinea pigs. Antigen was injected in guinea pigs along with either ribonucleic acid, deoxyribonucleic acid, lymphocytosis promoting factor or Hpopolysaccharide obtained from B. pertussis. It was concluded that the Hpopolysaccharide is the main active material responsible for the enhancement of IgE antibody production in guinea pigs.Keywords
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