Treatment of Gout by Reduction of Uric Acid Production

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Abstract
A study was made of the clinical and biochemical effects of 3 types of drug in the reduction of uric acid production: caparase, oroturic acid, and the xanthine oxidase inhibitor, allopurinol. A pilot experiment with 4 cases of gout was followed by a long-term study of 29 cases treated with allopurinol alone and in combination with anturan. The findings suggest that allopurinol with Anturan is valuable in treating severe cases of gout and in helping to prevent renal damage. It may also be used alone with advantage in certain selected cases.