Histone variants: deviants?
- 1 February 2005
- journal article
- review article
- Published by Cold Spring Harbor Laboratory in Genes & Development
- Vol. 19 (3) , 295-316
- https://doi.org/10.1101/gad.1272805
Abstract
Histones are a major component of chromatin, the protein-DNA complex fundamental to genome packaging, function, and regulation. A fraction of histones are nonallelic variants that have specific expression, localization, and species-distribution patterns. Here we discuss recent progress in understanding how histone variants lead to changes in chromatin structure and dynamics to carry out specific functions. In addition, we review histone variant assembly into chromatin, the structure of the variant chromatin, and post-translational modifications that occur on the variants.Keywords
This publication has 148 references indexed in Scilit:
- Evidence for nucleosome depletion at active regulatory regions genome-wideNature Genetics, 2004
- A Protein Complex Containing the Conserved Swi2/Snf2-Related ATPase Swr1p Deposits Histone Variant H2A.Z into EuchromatinPLoS Biology, 2004
- The cellular geography of Aurora kinasesNature Reviews Molecular Cell Biology, 2003
- The Crystal Structure of AF1521 a Protein from Archaeoglobus fulgidus with Homology to the Non-histone Domain of MacroH2AJournal of Molecular Biology, 2003
- Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine16 and spreading of heterochromatinNature Genetics, 2002
- A comprehensive two-hybrid analysis to explore the yeast protein interactomeProceedings of the National Academy of Sciences, 2001
- Histone H2A.Z Is Widely but Nonrandomly Distributed in Chromosomes of Drosophila melanogasterJournal of Biological Chemistry, 2000
- Histone H1 and Chromatin Higher-Order StructureCritical Reviews™ in Eukaryotic Gene Expression, 1997
- Association of histone H10 with a gene repressed during liver developmentNature, 1985
- A Histone Programme during the Life Cycle of the Sea UrchinEuropean Journal of Biochemistry, 1979