Effects of chronicβ‐carotene supplementation on vitamin K status in adults
- 1 January 1990
- journal article
- clinical trial
- Published by Taylor & Francis in Nutrition and Cancer
- Vol. 13 (4) , 263-269
- https://doi.org/10.1080/01635589009514068
Abstract
Plasma vitamin K concentrations and prothrombin coagulation activity were determined in 26 normal adults who had received daily (S‐carotene supplementation (0,15,30, or 60 mg) for six months. Neither plasma vitamin K nor coagulation activity were significantly decreased at any supplementation level. Thus, chronic β‐carotene supplementation, even at high daily doses, is not expected to result in clinical vitamin K deficiency. The data suggest separate mechanisms for intestinal absorption of β‐carotene and vitamin K.Keywords
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