Spontaneous Regression of Hepatic Metastases from a Carcinoma of the Colon

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Abstract
Spontaneous regression of malignant tumors, both primary and metastatic, which are proved by tissue diagnosis, is rare. A patient with hepatic metastases from a rectal carcinoma and with familial polyposis of the colon, proved by histologic study, who survived 10 years and in whom the hepatic metastases disappeared while a new colonic carcinoma developed is reported. Factors that may be responsible for the spontaneous regression of tumors are discussed. We believe that no current theory offers an adequate explanation why, as in our case, while one malignant tumor spontaneously regresses, another develops.