Simultaneous spectrophotometric determination of strychnine and yohimbine in pharmaceutical preparations
- 1 January 1986
- journal article
- Published by Royal Society of Chemistry (RSC) in The Analyst
- Vol. 111 (5) , 581-583
- https://doi.org/10.1039/an9861100581
Abstract
A spectrophotometric method is proposed for the simultaneous spectrophotometric determination of strychnine.HCl and yohimbine.HCl in pharmaceutical preparations. No preliminary separation step is required. The proposed method involves the use of the modified Vierordt equation. Accurate and reproducible results were obtained. The mean recoveries (six determinations) for strychnine.HCl and yohimbine.HCl were 98.8 ± 0.5% and 100.3 ± 0.8%, respectively. The method was applied to the determination of the two compounds in dosage forms and the results obtained were accurate and precise.Keywords
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