A new ribo-oligonucleotide block synthesized by phosphorylation with p-chlorophenyl N-phenylchlorophosphoramidate
- 1 January 1978
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 19,p. 824-825
- https://doi.org/10.1039/c39780000824
Abstract
Two types of nucleotides (5) and (6) have been synthesized as key intermediates for fully protected oligoribonucleotides which are suitable for elongation of the chain in the 3′- and 5′-directions by the triester method; condensation of these nucleotides yielded a fully protected dinucleotide [e.g.(7)] in high yield.This publication has 2 references indexed in Scilit:
- Studies on transfer ribonucleic acids and related compounds. 20. A new versatile ribooligonucleotide block with 2'-(o-nitrobenzyl) and 3'-phosphorodianilidate groups suitable for elongation of chains in the 3' and 5' directionsJournal of the American Chemical Society, 1978
- 4-Nitrophenyl phenyl phosphorochloridate: a new phosphorylating agent for oligonucleotide synthesisJournal of the Chemical Society, Chemical Communications, 1977