A xenogeneic monoclonal antibody recognizing specificities controlled byHLA-A andB alleles
- 1 December 1981
- journal article
- research article
- Published by Springer Nature in Immunogenetics
- Vol. 12 (1) , 615-626
- https://doi.org/10.1007/bf01561701
Abstract
In the present paper one reagent among the many prepared has been carefully studied. It is a xenogeneic monoclonal antibody, F10.13/13, obtained by immunizing mice with human peripheral blood lymphocytes. The splenocytes of the immunized mice were fused with a murine myeloma and the supernatants of the resulting Ig-secreting hybridomas were tested against appropriate targets. — F10.13/13 behaves in a very peculiar manner from the serological point of view and we think that it reacts with maximal affinity with an epitope expressed most strongly on HLA glycoproteins controlled by genesB8, B7, andAw19.This publication has 21 references indexed in Scilit:
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