Lactate Accumulation in Ischemic- and Anoxic-Isolated Rat Hearts Assessed by H-l Spectroscopy
- 1 August 1987
- journal article
- research article
- Published by Wolters Kluwer Health in Investigative Radiology
- Vol. 22 (8) , 638-641
- https://doi.org/10.1097/00004424-198708000-00004
Abstract
Proton magnetic resonance (MR) spectroscopy with homonuclear editing was used to assess lactate accumulation in ischemic and anoxic hearts perfused according to the Langendorff method. An increase in the lactate signal was observed after 5 minutes of ischemia and after 10 to 20 minutes of anoxia. This study demonstrates that proton MR spectroscopy can be used to monitor the time course of MR-visible lactate levels in ischemic and anoxic isolated rat hearts.This publication has 5 references indexed in Scilit:
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