Chronic granulomatous disease with cranial fungal osteomyelitis and epidural abscess

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Abstract
✓ A patient is described with osteomyelitis of the cranium and epidural abscess due toAspergillus fumigatusas the presenting manifestations of chronic granulomatous disease. The diagnosis was suggested by the unusual nature of the organism isolated and confirmed by appropriate laboratory studies. The details of diagnostic assessment and therapeutic management are discussed, and the central nervous system manifestations of chronic granulomatous disease are reviewed.