Quantification of the determinants of arterial hypoxemia in critically ill patients
- 1 August 1983
- journal article
- research article
- Published by Wolters Kluwer Health in Critical Care Medicine
- Vol. 11 (8) , 644-645
- https://doi.org/10.1097/00003246-198308000-00011
Abstract
A quantification of the determinants of arterial hypoxemia was performed in 376 cardiorespiratory measurements obtained from 180 critically ill patients. Statistical analysis showed that pulmonary venous admixture (Qsp/Qt) could explain only 48% of the Pao2variability in the sample of measurements taken (r2 = 0.48), while the effect of central venous O2 tension (PO2) brought the total explained PaO2 variability up to 82% (total r2 = 0.82). These findings imply that pulmonary function is not the only determinant of PaO2; the Pvo2-mediated effect of other cardiovascular and metabolic determinants must be recognized in the clinical setting.Keywords
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