The Effect of Personality on Placebo Response in Panic Patients

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Abstract
Twenty-eight patients who participated as a placebo group in a treatment study of panic disorders were studied to determine the effect of personality on study completion and outcome. Those subjects who completed only 3 weeks had significantly more pathological personality traits than those who continued in the study. For those continuing beyond 3 weeks, there were negative correlations between the paranoid and borderline personality traits and a global outcome measure. Spontaneous panic attacks were not affected by personality.

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