Role of Common Ions in Production of Increased Oxygen Consumption by Ouabain.

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Abstract
Ouabain causes increased O2 consumption of embryonic chick hearts in Locke solution and in Locke solutions with K or Ca contents radically increased or decreased. The effects of ouabain on the beat are exaggerated in K-deficient and Ca-excess solutions and reduced in K-excess solutions. The increased O2 consumption produced by ouabain is therefore not dependent on changes in the beat of the heart.