PRELIMINARY STUDIES WITH THE SENSITIVE CYTOCHEMICAL ASSAY FOR PARATHYROID HORMONE
- 1 October 1978
- journal article
- research article
- Published by Wiley in Clinical Endocrinology
- Vol. 9 (4) , 381-384
- https://doi.org/10.1111/j.1365-2265.1978.tb02224.x
Abstract
A modification of the cytochemical assay for parathyroid hormone (PTH) is described which permits the measurement of as little as 0.1 fg ml-1. Using this assay circulating concentrations in normal humans range between 1 and 30 pg ml-1 using a bovine PTH standard. Elevated values are found in hyperparathyroidism with reduced concentrations in hypoparathyroidism. Where detectable, PTH concentrations measured by radioimmunoassay are on average fourteen-fold higher than by cytochemical assay. No cross reactivity was found with AVP, calcitonin and 1,25 dihydroxy vitamin D in concentrations normally found in health or disease.This publication has 3 references indexed in Scilit:
- A SENSITIVE BIOASSAY OF PARATHYROID HORMONE IN PLASMAClinical Endocrinology, 1978
- A SENSITIVE BIOASSAY FOR ADRENOCORTICOTROPHIC HORMONE IN HUMAN PLASMAClinical Endocrinology, 1972
- SIMPLIFIED MATHEMATICS FOR MULTIPLE BIOASSAYSActa Endocrinologica, 1960