A Search for Virus-Inactivating Substances Among Microorganisms

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Abstract
150 organisms, comprising bacteria, fungi and actinomycetes, were isolated from straw-compost, manure, soil, drainage material and soil enriched with virus concentrates, and were tested for antiviral activity in vitro. 3 of these organisms gave indications of possible inactivation of some of the fowl pox virus, and in 1 case, of the laryngo-tracheitis virus. The active principle of 1 of these organisms was actino-mycin A, an antibacterial subst. toxic to animals. The antiviral potentialities of the other 2 organisms were not definitely detd.