Haploinsufficiency of yeast FEN1 causes instability of expanded CAG/CTG tracts in a length-dependent manner

This publication has 33 references indexed in Scilit:

• Fen1 does not control somatic hypermutability of the (CTG)_n· (CAG)_n repeat in a knock‐in mouse model for DM1
  FEBS Letters, 2006
• Replication fork dynamics and dynamic mutations: the fork-shift model of repeat instability
  Trends in Genetics, 2005
• Structure-Forming CAG/CTG Repeat Sequences are Sensitive to Breakage in the Absence of Mrc1 Checkpoint Function and S-Phase Checkpoint Signaling: Implications for Trinucleotide Repeat Expansion Diseases
  Cell Cycle, 2004
• Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis
  Human Molecular Genetics, 2003
• Mutations in Yeast Replication Proteins That Increase CAG/CTG Expansions Also Increase Repeat Fragility
  Molecular and Cellular Biology, 2003
• Nuclease-Deficient FEN-1 Blocks Rad51/BRCA1-Mediated Repair and Causes Trinucleotide Repeat Instability
  Molecular and Cellular Biology, 2003
• DNA Ligase I Competes with FEN1 to Expand Repetitive DNA Sequences in Vitro
  Journal of Biological Chemistry, 2002
• Origins of instability
  Nature, 2001
• Inhibition of Flap Endonuclease 1 by Flap Secondary Structure and Relevance to Repeat Sequence Expansion
  Published by Elsevier ,2000
• Repeat expansion — all in flap?
  Nature Genetics, 1997