POLYRADICULONEURITIS (GUILLAINBARRÉ SYNDROME)

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Abstract
During recent years two valuable therapeutic agents, sulfanilamide and fever therapy, have been added to the armamentarium in the treatment of disease. However, like other therapeutic measures, they may be accompanied or followed by undesirable effects in a certain percentage of cases. It is often difficult to decide, when two therapeutic agents are used concomitantly or consecutively, which agent is responsible for the favorable effect on the disease or, in some instances, even the undesirable complication. Numerous toxic manifestations have been described following the use of sulfanilamide and its derivatives. Reports indicating a toxic action of sulfanilamide on the peripheral nervous system are few. Ornsteen and Furst1reported a case of peripheral neuritis which followed the ingestion of 130 Gm. of sulfanilamide. Janet2observed one case of multiple neuritis of the arm and thorax which lasted only three days. Waugh3recently reported a case of neuritis of

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