Prenatal identification of a deleted Y chromosome by cytogenetics and a Y-specific repetitive DNA probe
- 1 July 1984
- journal article
- case report
- Published by Springer Nature in Human Genetics
- Vol. 67 (2) , 222-224
- https://doi.org/10.1007/bf00273007
Abstract
A very small sex chromosome was identified prenatally as a Y chromosome by using molecular hybridization in conjunction with conventional cytogenetics techniques. The combination of R-banding, Q-banding, distamycin-DAPI staining suggested that the chromosome might be a de novo deletion of the Y chromosome as the father's Y chromosome was normal. Restriction enzyme analysis of amniotic fluid cell DNA using a Y chromosome repetitive probe confirmed the origin of this chromosome.Keywords
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