LITHIUM: ITS EFFECT ON HUMAN SPERMATOZOA, RAT TESTICULAR TISSUE AND UPON RATS IN VIVO
- 1 May 1949
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 157 (2) , 177-183
- https://doi.org/10.1152/ajplegacy.1949.157.2.177
Abstract
LiCl, in low concn., inhibits the aerobic and anaerobic glycolysis of human spermatozoa and destroys their motile activity. The Li ion, in contrast, stimulates the aerobic lactic acid production of rat testicular tissue without affecting the anaerobic glycolysis or the respiration of that tissue. The acute and chronic effects of LiCl injd. subcut. into male rats are described. It is shown that the symptoms induced in rats are strikingly similar to those found in Li toxicity in man.Keywords
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