Stress analgesia: the opioid analgesia of long swims suppresses the non-opioid analgesia induced by short swims in mice
- 1 July 1991
- journal article
- Published by Wolters Kluwer Health in Pain
- Vol. 46 (1) , 89-95
- https://doi.org/10.1016/0304-3959(91)90038-y
Abstract
In mice, room temperature swimming for as short a period as 15 sec has been found to induce a non-opioid analgesia with a time course of 10–12 min. As the duration of the swim is increased, an opioid analgesia develops with a longer persistence (25–30 min); the development of the opioid analgesia appears to suppress the expression of the non-opioid analgesia so that none of the latter is evident after 3 min swims. The characteristics of the tail-flick nociceptive test are also described.Keywords
This publication has 17 references indexed in Scilit:
- Nociceptive Sensitivity/Behavioral Reactivity Regulation in Rats During Aversive States of Different Nature: Its Mediation by Opioid PeptidesInternational Journal of Neuroscience, 1989
- Swim stress reduces chronic pain in mice through an opioid mechanismNeuroscience Letters, 1987
- Naloxone hyperalgesia and stress-induced analgesia in ratsLife Sciences, 1983
- Effects of electric footshock on barviturate sensitivity, nociception and body temperature in miceEuropean Journal of Pharmacology, 1983
- The characteristics of the opioid-related analgesia induced by the stress of swimming in the mouseNeuroscience Letters, 1982
- Lack of effect of naloxone on autoanalgesiaPharmacology Biochemistry and Behavior, 1979
- Naloxone increases pain perception in rats and miceLife Sciences, 1979
- ENHANCEMENT OF A NOCICEPTIVE REACTION BY OPIOID ANTAGONISTS IN MICEBritish Journal of Pharmacology, 1978
- Hyperalgesia Induced by Naloxone Follows Diurnal Rhythm in Responsivity to Painful StimuliScience, 1977
- THE HEAT REGULATION OF SMALL LABORATORY ANIMALS AT VARIOUS ENVIRONMENTAL TEMPERATURESAmerican Journal of Physiology-Legacy Content, 1940