NON‐ENDOCRINE CARCINOID TUMOUR OF THE UTERINE CERVIX; ASPECTS OF DIAGNOSIS AND TREATMENT

Abstract
A case of primary well-differentiated carcinoid tumor of the uterine cervix in a 62 yr old Chinese women without endocrine symptoms is reported and its clinico-pathological features, ultrastructure and response to radiotherapy discussed. Clinically the tumor was presented as a polypoid lesion. The initial diagnosis was squamous carcinoma of cervix stage Ib and the patient was treated with radiotherapy. The tumor disappeared after application of 1st intracavitary irradiation of 4500 mg/h. After completion of 9000 mg/h, Wertheim hysterectomy followed and no residual tumor was found. Retrospective staining of the pre-irradiation cervical tumor by Grimelius method was positive for argyrophilic granules, and EM study demonstrated neurosecretory granules in the cytoplasm and established the diagnosis.