High‐frequency ultrasound measurement of patch test reactions

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Abstract
53 patients who produced 34 positive pinch test reactions (±15, + 10), ++ 4, + 4,+++5) had their reactions read by a high‐frequency pulsed ultrasonic (A‐scan) dermal depth detector with a resolution of 0.05 mm. The positive reactions were compared with both random and regional controls. The machine could not differentiate between + or ± reactions from the control readings. However, for 75% of ++ cases and 80% of +++ cases, a significant change was confirmed by the detector. It is concluded that the high‐frequency ultrasound method is of little use in confirming or quantifying of positive patch test results.