New Insights into the Pathogenesis of Insulin Resistance in Humans Using Magnetic Resonance Spectroscopy
Open Access
- 1 February 2006
- Vol. 14 (S2) , 34S-40S
- https://doi.org/10.1038/oby.2006.280
Abstract
Insulin resistance plays a major role in the pathogenesis of type 2 diabetes, yet despite much effort, the underlying factors that are responsible for it are poorly understood. In this review, we focus on some recent advances in our understanding of the pathogenesis of insulin resistance in humans that have been made using magnetic resonance spectroscopy.Keywords
This publication has 49 references indexed in Scilit:
- Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 DiabetesNew England Journal of Medicine, 2004
- Global and societal implications of the diabetes epidemicNature, 2001
- Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of IkkβScience, 2001
- Prevention of fat-induced insulin resistance by salicylateJournal of Clinical Investigation, 2001
- Aging-Dependent Large Accumulation of Point Mutations in the Human mtDNA Control Region for ReplicationScience, 1999
- Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1Cell, 1999
- Pathogenesis of NIDDM: A Balanced OverviewDiabetes Care, 1992
- Quantitation of Muscle Glycogen Synthesis in Normal Subjects and Subjects with Non-Insulin-Dependent Diabetes by13C Nuclear Magnetic Resonance SpectroscopyNew England Journal of Medicine, 1990
- Impaired Glucose Tolerance as a Disorder of Insulin ActionNew England Journal of Medicine, 1988
- THE GLUCOSE FATTY-ACID CYCLE ITS ROLE IN INSULIN SENSITIVITY AND THE METABOLIC DISTURBANCES OF DIABETES MELLITUSPublished by Elsevier ,1963